1H-Indole-2-carboxylic acid, 6-chloro-7-fluoro- - Names and Identifiers
1H-Indole-2-carboxylic acid, 6-chloro-7-fluoro- - Physico-chemical Properties
Molecular Formula | C9H5ClFNO2
|
Molar Mass | 213.59 |
Density | 1.635±0.06 g/cm3(Predicted) |
Boling Point | 455.4±40.0 °C(Predicted) |
pKa | 4.11±0.30(Predicted) |
1H-Indole-2-carboxylic acid, 6-chloro-7-fluoro- - Upstream Downstream Industry
1H-Indole-2-carboxylic acid, 6-chloro-7-fluoro- - Introduction
1H-Indole-2-carboxylic acid, 6-choro-7-fluoro-is an organic compound with the chemical formula C9H5ClFNO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 1H-Indole-2-carboxylic acid, 6-chloro-7-fluoro-is a white or off-white solid.
-Melting point: about 170-172 degrees Celsius.
-Solubility: It dissolves in some organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
-Research field: 1H-Indole-2-carboxylic acid, 6-choro-7-fluoro-can be used as chemical intermediates and play an important role in organic synthesis.
-Drug research: It is also used in drug research, such as intermediates for the synthesis of new anti-cancer drugs.
Method:
- 1H-Indole-2-carboxylic acid, 6-chloro-7-fluoro-has many preparation methods, and the common methods include the following steps:
1. Starting with 6-chloro -7-fluoro -1H-indole.
2. Carboxylation of indole using an appropriate reagent to introduce a carboxylic acid group.
3. Through acid-catalyzed reaction, chlorine and fluorine substituents are introduced into specific positions of indole to obtain the target product.
Safety Information:
- 1H-Indole-2-carboxylic acid, 6-choro-7-fluoro-specific safety information may vary from supplier to supplier and condition, should refer to the relevant safety data sheet.
-When using or handling the compound, observe appropriate laboratory procedures, use personal protective equipment, and follow relevant workplace safety regulations.
-Care should be taken to avoid inhalation, ingestion or skin contact with the substance and to avoid its entry into the eyes.
-When storing and handling this compound, pay attention to fire and explosion prevention measures, and handle and dispose of it in accordance with local regulations.
Last Update:2024-04-09 19:05:54